In 1933, after leaving Dogville, Grace Margaret Mulligan sees a slave being punished at a cotton farm called Manderlay. Officially slavery is illegal and Grace stands up against the owners of the farm. She stays with some gangsters in Manderlay and tries to influence the situation. But when harvest time comes Grace sees the social and economic reality of Manderlay.
After the death of her husband, the mother of Julie, Jack, Sue and Tom begins to suffer from a mysterious illness. Aware that she is going to have to go into hospital she opens a bank account for the children, so that they can be financially self-sufficient and will be able to avoid being taken into care by the authorities. Unfortunately she also dies and Julie and Jack (the older, teenage children) decide to hide her body in the basement so that they can have free reign of their household. Soon Tom has taken to dressing as a girl whilst Sue has become increasingly reticent, confiding only to her diary, meanwhile Jack and Julie sense an attraction developing for each other. However Julie's new beau, Derek, threatens to unearth the many dark secrets within this family as he becomes increasingly suspicious of Jack.
School student and her European-born grandmother share sad stories of their lives.
Clara and her two sons escape from her abusive husband with little more than their car and plan to start over in New York. After the car towed away, the family meets Alice, who gets them into an emergency shelter. While stealing food at a Russian restaurant called ‘Winter Palace’, Clara meets Marc, who has been given the chance to help the old eatery regain its former glory. The ‘Winter Palace’ soon becomes a place of unexpected encounters between people who are all undergoing some sort of crisis and whom fate has now brought together.